TNF [化] 肿瘤坏死因子
tnf[ noun ]
a proinflammatory cytokine that is produced by white blood cells (monocytes and macrophages); has an antineoplastic effect but causes inflammation (as in rheumatoid arthritis)
<noun.substance>
- The body naturally produces TNF in response to infection.
- The hybrid protein was the product of the gene for interferon, a protein the body naturally produces to fight viruses and cancer, and the gene for tumor necrosis factor, or TNF, another natural human protein that has anti-cancer effects.
- Preparations for the experiment began five months ago, when Dr. Rosenberg's team surgically removed a piece of this patient's tumor and implanted the gene for tumor-necrosis factor, or TNF, a natural protein that erodes cancer.
- Monday, Dr. Rosenberg told the panel's Human Gene Therapy Subcommittee that TNF has "almost been miraculous in what it can do" in reducing tumors in mice.