an event in which one thing is substituted for another
<noun.event> the replacement of lost blood by a transfusion of donor blood
the act of changing the arrangement of a given number of elements
<noun.act>
complete change in character or condition
<noun.act> the permutations...taking place in the physical world
act of changing the lineal order of objects in a group
<noun.act>
Permutation \Per`mu*ta"tion\, n. [L. permutatio: cf. F. permutation. See {Permute}.] 1. The act of permuting; exchange of the thing for another; mutual transference; interchange.
The violent convulsions and permutations that have been made in property. --Burke.
2. (Math.) (a) The arrangement of any determinate number of things, as units, objects, letters, etc., in all possible orders, one after the other; -- called also {alternation}. Cf. {Combination}, n., 4. (b) Any one of such possible arrangements.
3. (Law) Barter; exchange.
{Permutation lock}, a lock in which the parts can be transposed or shifted, so as to require different arrangements of the tumblers on different occasions of unlocking.
"Right Behind the Flag" by Kevin Heelan is one of those mysterious little comedies that starts strong and then fades in the finish, in this case because of a murky plot permutation involving drugs.