pain receptor 痛觉感受器
- Objective : Buprenorphine, an agonist-antagonist of opioid receptor, is widely used in chronic pain therapy .
目的:丁丙诺啡是阿片受体激动-拮抗剂,已被广泛应用于临床慢性疼痛治疗; - But neither treatment eased pain in mice that lacked a cell-surface receptor through which adenosine exerts its effects.
但是两种疗法对于缺乏细胞表面受体的老鼠都起不到缓解疼痛的作用,因为腺苷是通过细胞表面受体来发挥作用的。 - Conclusion: Melatonin can change the responses of pain neurons to pain stimulation via opioid receptor in the LHb, which might be one of analgesic mechanisms by MEL.
结论:褪黑色素可通过作用于外侧缰核的阿片受体而影响其痛相关神经元对痛刺激的反应,这可能是褪黑色素中枢镇痛机制之一。
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