Conclusions: The experiments demonstrated that very potent effects could be achieved through the pro-transition-state hapten strategy. 结论:实验证明了该半抗原设计策略的有效性。
It may be an alternative strategy for hapten design of antibody catalysis involved in the hydrolysis of nucleotides, esters, carbamates, amides and peptides. 该半抗原设计策略还可能应用于能诱生催化磷()二酯水解的抗体酶的半抗原设计,以及应用于有类似酯酶、胺酶、酶或核苷酸活性的抗体酶的研究。
Methods: A new hapten design strategy termed“ pro-transition-state” hapten strategy was proposed and a novel hapten and relative synthesized antigens were designed and 方法:提出“潜过渡态”半抗原设计策略,并据此设计、成了新型半抗原和人工抗原。