类碱基 [
lèi jiǎn jī]
base analogue
- 为了找出驱动和旅客突变间的差别,研究人员将921种单碱基替换突变分成两类:非同义(改变一个氨基酸)或同义(对氨基酸序列没有影响)。
To discriminate between driver and passenger mutations, the authors annotated the 921 single-base substitutions that they identified as being either non-synonymous (changing an amino acid) or synonymous (having no effect on the protein sequence).
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