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 enzyme ['enzaim]   添加此单词到默认生词本
n.

[化] 酶

[医] 酶


  1. An enzyme that promotes the passage of a substance across a cell membrane.
    透性酶激活另一种物质穿透细胞膜的一种酶
  2. A substance, especially an enzyme, that initiates or modifies the rate of a chemical reaction in a living body; a biochemical catalyst.
    生物催化剂能在活的体内产生化学反应或改变生物体内化学反应速度的物质,尤指酶;生物化学催化剂
  3. Any of the chemically distinct forms of an enzyme that perform the same biochemical function.
    同工酶,同功酶具有相同的生化功能的一种酶的不同化学形式中的任一种


enzyme
[ noun ]
any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions
<noun.substance>


enzyme \en"zyme\ ([e^]n"z[imac]m), n. [Pref. en- (Gr. 'en in) +
Gr. zy`mh leaven.] (Physiol. Chem.)
A protein produced by a living organism, capable of
catalyzing a chemical reaction. Almost all processes in
living organisms require some form of enzyme to cause the
reactions to occur at a rate sufficient to support life.
There are a very wide variety of enzymes, each specifically
catalyzing a different chemical reaction, the sum of which
cause the bulk of the physiological changes observed as life
processes. Enzymes, like most proteins, are synthesized by
the protein-synthetic mechanism of the living cell, at
special sites on ribosomes, using the genetic information in
messenger RNA transcribed from the genetic instructions
stored as nuleotide sequences in the DNA (or in some viruses,
the RNA) of the genome. Some examples of enzymes are: pepsin,
diastase, rennet, DNA polymerase, invertase, glucose oxidase,
protease, and ribonuclease. There are many other types of
enzyme.
[1913 Webster +PJC]

Note: The 1913 Webster defined an enzyme as:
An unorganized or unformed ferment, in distinction from
an organized or living ferment; a soluble, or chemical,
ferment.
[PJC]

  1. By measuring levels of the enzyme, doctors may be able to target therapy to women who could benefit the most.
  2. The virus has been disabled and is no longer infectious, but is a vehicle to get the normal gene into the cells where it produces the required enzyme.
  3. The company said that the new test is an "enzyme immunoassay" that detects at least one key antigen, or protein, produced by the AIDS virus.
  4. The Boehringer and Merck drugs, however, both work against the reverse transcriptase enzyme in a manner that differs significantly from AZT, the only drug now approved for use against the virus.
  5. It has a remarkable effect." Dr. Crystal takes credit for putting Genentech's DNase into aerosol form. He said the idea of using DNase has been around since the 1950s or so, but that the bovine form of the enzyme caused allergic reactions.
  6. The therapy would not be a permanent cure, Blaese said, since the enzyme would be produced only as long as the genetically manipulated cells live.
  7. The afflicted children were born with a gene that does not produce the enzyme adenosine deaminase, or ADA, which is essential for an immune system to function normally This leaves them vulnerable to infections and diseases most people can fight off.
  8. Wellcome of the UK has an experimental compound aimed at a different enzyme, which would be taken by mouth.
  9. This chemical, called captopril, became the first inhibitor of angiotensin-converting enzyme, or ACE inhibitor.
  10. One reason researchers think blacks are less responsive to ACE inhibitors, for instance, is that blacks typically already have low levels of renin, the enzyme the drug blocks.
  11. Dr. Scolnick said that in April, Merck found a chemical that blocked the enzyme after testing about a thousand compounds developed over the years.
  12. When used in mice, researchers were able to transfer bacterial genes that produce an enzyme.
  13. The possibility of using drugs to inhibit the acetylcholinesterase enzyme, thereby repairing the shortage of acetylcholine in the Alzheimer patient's brain, was and continues to be the most promising avenue of applied research.
  14. The company said the drug is the first treatment for directly correcting an inherited enzyme deficiency disease.
  15. The Warner-Lambert spokesman said the company's top research official spoke to Dr. Temple about the enzyme hypothesis Friday and was "intrigued" by it.
  16. Scientists identified a gene that is activated in normal cells surrounding invasive breast cancers, spurring the normal cells to produce an enzyme that may help cancer cells spread from the original tumor.
  17. Current successful antihypertensive medications, known as angiotensin converting enzyme (ACE) inhibitors, block the second step of the process leading to raised blood pressure and hypertension.
  18. Benenson said that most laboratories first test for the virus using an enzyme immunoassay, or EIA, test.
  19. "The staph organism quickly becomes resistant to antibiotics by producing an enzyme that renders the antibiotic ineffective," Young said.
  20. The main target is acetylcholine (a neurotransmitter essential for memory) in which the Alzheimer's brain is severely deficient. A class of medicines called aminoacridines achieve this by blocking the enzyme that destroys acetylcholine in the brain.
  21. The child, who was not identified, has a rare genetic disease called ADA deficiency - a defective gene which means her immune system does not function adequately because the enzyme it produces is defective.
  22. The biotechnology company said it is producing a genetically engineered version of the substance, an enzyme called reverse transcriptase, and supplying it to NIH researchers under the collaboration agreement.
  23. The researchers took skin cells from rats and inserted genes to produce an enzyme called tyrosine hydroxylase, which serves as a catalyst to make the cell produce L-dopa.
  24. Dr. Cordis's group recently developed a chemical that blocks the enzyme in normal men and is studying it as a potential drug to treat the more common prostate problem.
  25. The tomato is made with a gene that reduces the expression of a naturally occurring enzyme that otherwise cause the breakdown of pectin in fruit.
  26. The Harvard research identified and described an enzyme called isomerase which plays a role in vision.
  27. Some goes to ICI Agrochemicals but most is sold to competitors. The key to the process is an enzyme which ICI produces from genetically engineered bacteria.
  28. The company said its tag DNA polymerase is a key component of its geneamp polymerase chain reaction technology and is one of the largest selling enzyme products in the molecular biology research market.
  29. They also note that enzyme problems are rare and disappear when the drug is stopped and that Voltaren doesn't have a record of causing a higher rate of liver problems than other drugs of its type.
  30. Researchers say the enzyme that ordinarily breaks down fat can't break down SPE since the substance includes more fatty acids than natural fats; P&G says tests in animals and humans haven't produced any evidence that traces of SPE remain in the body.
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